Warning - JavaScript advice from 2010 is to be taken with a large grain of salt. This is here for posterity.
Presentation given at the 2010 ESRI Developer Summit.
Slides are available here: http://github.com/kvangork/OOJS-Presentation/blob/master/OOJS.pdf
Source code here: http://github.com/kvangork/OOJS-Presentation